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13:16 May 20, 2013 Into (AGI) – Washington, May 20 – In 2008, researchers at the University of Southern Denmark showed that the neuroleptic thioridazine, a drug previously used to treat schizophrenia, was a powerful weapon against antibiotic-resistant bacteria, such as staphylococci (Staphylococcus aureus). Now the team has discovered how thioridazine acts on bacteria resistant, huge problem felt across the world with twenty-five – 50 per cent of the inhabitants of southern Europe-resistant staphylococci.
The research team has tested the ‘ antipsychotic drug on the bacteria staphylococcus and found that it works by weakening the bacterial cell wall. “When we treat only the bacteria with antibiotics but nothing happens if we add the antibiotic thioridazine witness a remarkable change of scenery: Thioridazine weakens the bacterial cell wall, eliminating the glycine (an amino acid) from the cell wall. In the absence of glycine, antibiotics are able to attack the weakened cell wall and kill the bacteria, “said Janne Kudsk Klitgaard of the Department of Biochemistry and Molecular Biology in the article published in the journal ‘PLoS ONE’. (AGI).
IntoThe research team has tested the ‘ antipsychotic drug on the bacteria staphylococcus and found that it works by weakening the bacterial cell wall. “When we treat only the bacteria with antibiotics but nothing happens if we add the antibiotic thioridazine witness a remarkable change of scenery: Thioridazine weakens the bacterial cell wall, eliminating the glycine (an amino acid) from the cell wall. In the absence of glycine, antibiotics are able to attack the weakened cell wall and kill the bacteria, “said Janne Kudsk Klitgaard of the Department of Biochemistry and Molecular Biology in the article published in the journal ‘PLoS ONE’. (AGI).
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